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Symbol
Name
ID

Pax4
paired box 4
MGI:97488

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Diabetes mellitus	Maturity-onset diabetes of the young	Type II diabetes mellitus	Beta-cell dysfunction
Disease(s) Associated with PAX4	Diabetes mellitus	Maturity-onset diabetes of the young	Type II diabetes mellitus	Beta-cell dysfunction
diabetic ketoacidosis
maturity-onset diabetes of the young type 9
type 1 diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes		endocrine/exocrine gland phenotype	abnormal pancreatic islet morphology	increased pancreatic alpha cell number	decreased pancreatic beta cell number	absent pancreatic beta cells	absent pancreatic delta cells	abnormal pancreas morphology	abnormal pancreas secretion
Availability	Mouse Genotype	endocrine/exocrine gland phenotype	abnormal pancreatic islet morphology	increased pancreatic alpha cell number	decreased pancreatic beta cell number	absent pancreatic beta cells	absent pancreatic delta cells	abnormal pancreas morphology	abnormal pancreas secretion
	Pax4^{tm1(cre/ERT2)Sosa}/Pax4^{tm1(cre/ERT2)Sosa}
	Pax4^tm1Pgr/Pax4^tm1Pgr	*
	Pax4^tm1Pgr/Pax4^tm1.1Aman Tg(CMV-cre)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23